After the establishment of the Polish Red Cross Society, 4 large Regional Committees were created: Lesser Poland, Greater Poland, South-Eastern, and Polesie-Minsk, with main centers in Krakow, Lviv, Poznań, and Warsaw. The creation of these regions was recorded in the first Statute of the PTCK from 1919.

After the Red Army entered Polish territory, thousands of Polish soldiers and representatives of the intelligentsia were taken into Soviet captivity. The NKVD placed them in special camps, having previously organized a selection for officers, non-commissioned officers, and privates.

During the interwar period, the Polish Red Cross held a privileged position in the state, benefiting from the provisions of the law granting it donations from the sale of tickets for various types of shows, performances, concerts, spectacles, competitions, etc.

The originator and initiator of the "Red Rose" Rallies was Kazimierz Nowak, a longtime President of the HDK PCK Club operating at the Krakow steelworks. The first meeting was organized in 1977 in Tenczynek and was called the I Gathering of the "Red Rose".

„Let the Red Cross not be red like an unhealed wound, but let it adorn the red of a heart that loves its neighbor and brings him active help” - Gen. Józef Haller, 1919

During the interwar period, the Polish Red Cross began its celebrations on June 1st, and there was also a time when the Red Cross Week started on May 26th, on Mother's Day (probably related to the cult of the mother of Józef Piłsudski).

Available historical sources show that the PCK Week was already celebrated by the Galician Red Cross Society led by Father Paweł Sapieha. The tradition was borrowed from the celebrations of the Austrian Red Cross.

Since the beginning, the badges have been issued by the Polish Red Cross, as stated on the certificate "In recognition of the most beautiful humanitarian gift – the selfless donation of blood" and this has not changed over the years.

In 1935, the Polish Red Cross began organized activities for blood transfusion, including the organization of courses for doctors and the promotion of blood donation. The first Blood Transfusion Institute in Poland was also established.

Today is a special holiday – Mother's Day. There's no way not to mention the celebrations of this day at the Polish Red Cross over the last 100 years. "Mother's Day" was one of the most important holidays celebrated by the youth of the Polish Red Cross during the interwar period.

The PCK during the Second World War was engaged on a large scale in organizing aid for the civilian population, while simultaneously dealing with many difficulties, mainly financial and harassment from the German authorities.